منابع مشابه
Muscle Differentiation: How Two Cells Become One
A key feature of myogenesis is the fusion of myoblasts to form multinucleate myotubes. Recent work in Drosophila has uncovered a collection of genes that operate at different stages of this process. Some interactions between them have been described that begin to define links from outside the cell via the plasma membrane to the cytoskeleton. Future studies will establish the extent to which the...
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Marriage is an intensely practical matter. As a result, the subject of marriage is commonly taken up in practical teaching or in counselling rather than in a study of biblical doctrine. We have a strong biblical basis for this. In Paul’s letters, the subject of marriage in taken up in the practical rather than doctrinal sections of his letters. In this study, we will look at marriage from a doc...
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CENP-A containing nucleosomes epigenetically specify centromere position on chromosomes. Deposition of CENP-A into chromatin is mediated by HJURP, a specific CENP-A chaperone. Paradoxically, HJURP binding sterically prevents dimerization of CENP-A, which is critical to form functional centromeric nucleosomes. A recent publication in The EMBO Journal (Zasadzińska et al, 2013) demonstrates that H...
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In this paper we set up a model of interacting drug epidemics by taking the ”direct-product” of variations on a one-dimensional optimal control model that exhibits a so-called DNSS or Skiba threshold. Such a threshold reflects in drug policy the well-established paradigm of ”eradication vs. accommodation”; that is, depending on the initial state, stabilizing a drug market at either a low or a h...
متن کاملHow does one become a family physician?
No doubt there are as many reasons for becoming a family physician as there are family physicians. Some would say that they inherited the gene from their fathers or mothers, who were family physicians before them; it was their destiny. Some remember physicians who inspired them to pursue this path by setting a wonderful example: their own family physicians or the physicians who practised in the...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 1999
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.85.3.219